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Buy Ultram Online It is the brand name for tramadol, like an opioid. It works in the brain and the spine (central nervous system) to relieve pain. Ultram helps treat moderate to severe pain in adults. You can conveniently ultram side effects. Ultram is a schedule IV drug that can be used for treating mild to severe pain, both acute and chronic. The effect usually begins after one hour and lasts up to 2 two hours when taken orally.